Tetraglycylferrichrome - the first heptapeptide ferrichrome
نویسندگان
چکیده
منابع مشابه
Microbial Degradation of the Ferrichrome Compounds.
An unidentified Pseudomonas capable of growth on ferrichromes as sole sources of carbon and nitrogen was isolated by enrichment culture on ferrichrome A. The spectral shifts observed for the culture supernatant fluids and the degradation products which accumulated in the culture media during growth on these compounds indicated that initially the cyclic peptide rings are broken to yield simpler ...
متن کاملAn assay method for ferrichrome.
The isolation, chemical nature, and biological activity of the new iron compound ferrichrome have been reported elsewhere (l-3). Biochemical interest in ferrichrome centers, at present, around (a) its growth factor activity for PiZobolusl and (b) its possible relationship to cytochrome c formation in Ustilago sphaerogena. A suitable assay method for ferrichrome has been much desired as an aid t...
متن کاملFactors affecting the microbial production of ferrichrome.
The isolation and general properties of ferrichrome have been reported elsewhere (l-3). Studies on the fundamental biological mechanism of action of this compound may be directed into one or both of two channels. The substance may be examined for its mode of action by using an organism for which it shows growth factor activity, i.e. Pilobolus kleinii. Alternatively, it may be studied in an orga...
متن کاملStudies on the metabolic function of the ferrichrome compounds.
Ferrichrome is a representative member of a group of microbial products which show very intense growth factor activity when tested with a small number of selected fungal and bacterial species (1). Some of the members of this group of compounds, e.g. aspergillic acid (2), nocardamin (3), and grisein (albomycin) (4), are potent antibiotics against certain strains of microorganisms. Although the u...
متن کاملTotal synthesis of cyclic heptapeptide Rolloamide B.
The first total synthesis of Rolloamide B, a cyclic proline-enriched heptapeptide, is reported. This work features solution phase benzotriazole-mediated peptide synthesis ligating native amino acids.
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1984
ISSN: 0014-5793
DOI: 10.1016/0014-5793(84)81016-9